How bipolar disorder is tested on the NCLEX-RN
Items cross Psychosocial Integrity, Safety, and Pharmacological Therapies.
Nursing care in acute mania
The client may not notice hunger, thirst, or fatigue.
Lithium levels and toxicity
Know the warning signs at each level.
| Expected side effects | Report (possible toxicity) |
|---|---|
| Fine hand tremor | Coarse tremor |
| Thirst, increased urination | Persistent vomiting or diarrhea |
| Mild nausea early in therapy | Confusion, unsteady gait, slurred speech |
| Weight gain | Muscle twitching, seizures |
Long-term monitoring includes kidney and thyroid function.
Sodium, fluids, and interactions
Lithium and sodium compete for reabsorption in the kidney.
| Situation | Effect on lithium level | Nursing action |
|---|---|---|
| Low-salt diet, sweating, vomiting, diarrhea | Rises | Maintain salt and fluids; hold and notify if ill |
| Thiazide diuretics | Rises | Check with provider; monitor levels |
| NSAIDs (ibuprofen) | Rises | Teach to ask before using OTC pain relievers |
| ACE inhibitors | Rises | Monitor levels |
| High salt intake | May fall | Keep intake consistent |
Acetaminophen is generally preferred over NSAIDs for minor pain, per the provider.
NGN-style case and teaching
A classic item links illness to rising lithium levels.
A client on lithium has had vomiting and diarrhea for 2 days, now has a coarse tremor and is confused. What should the nurse do?
- Recognize cues: fluid and sodium loss, coarse tremor, confusion.
- Analyze: dehydration raised the lithium level; this suggests toxicity.
- Hold the next dose and notify the provider.
- Anticipate a stat lithium level, electrolytes, renal function, and IV fluids.
Answer. Hold the lithium, notify the provider, and anticipate a stat level and fluids.
- Drink about 2–3 L of fluid daily and keep salt intake consistent.
- Call the provider if vomiting, diarrhea, fever, or heavy sweating occurs.
- Avoid NSAIDs unless approved; tell all providers you take lithium.
- Keep appointments for blood levels; take doses at the same times each day.
- Lithium can harm a developing fetus; discuss pregnancy plans with the provider.