How corticosteroids are tested on the NCLEX-RN

Items cover Pharmacological Therapies (adverse effects, administration) and Reduction of Risk Potential (glucose, infection, adrenal suppression).

Long-term steroid effectsMetabolicHyperglycemia,weight gain,moon faceImmuneInfection,masked feverFluidsFluidretention, lowK⁺, HTNBone andskinOsteoporosis,thin skin, slowhealingMindInsomnia, moodswings
Adverse effects rise with dose and duration.

Monitoring a client on corticosteroids

Each adverse effect has a matching nursing assessment.

MonitorFinding to reportReason
Blood glucoseElevated readingsSteroid-induced hyperglycemia; insulin may be needed
Weight, edema, BPRapid gain, rising BPSodium and water retention
PotassiumLowMineralocorticoid effect
Signs of infectionSubtle: fatigue, sore throat, wound changesFever and redness may be masked
GIEpigastric pain, black stoolsGI bleeding risk, higher when combined with NSAIDs
Mood and sleepAgitation, insomnia, depressionSteroid psychiatric effects

Report changes per facility policy.

Tapering and adrenal crisis

The most important safety point: long-term steroids must not be stopped suddenly.

Long-termdoseWeeks or moreSuppressionAdrenals make lesscortisolAbrupt stopOr major stressAdrenalcrisisHypotension, shock
Why taper. Clients may also need extra ("stress") doses during surgery or serious illness, as ordered.
CirculationHypotension, tachycardia, shockLabsLow sodium, low glucose; high K⁺ mainly in primaryadrenal failureGINausea, vomiting, abdominal painNeuroWeakness, confusion
Adrenal crisis is an emergency treated with IV hydrocortisone and fluids, as ordered.

Administration by route

Route-specific teaching appears often.

RouteNursing point
OralGive with food; morning dosing for once-daily regimens
InhaledRinse mouth and spit after use; use a spacer if prescribed; not a rescue drug
IVMonitor glucose and BP; used for acute severe conditions
TopicalThin layer; avoid large areas or occlusion unless prescribed

Inhaled steroids are controllers; a short-acting bronchodilator is the rescue drug.

Client teaching and an NGN-style case

Long-term users need clear self-care instructions.

  • Never stop the medication suddenly; follow the taper schedule exactly.
  • Wear medical identification if on long-term therapy.
  • Avoid people who are sick; report signs of infection early.
  • Monitor glucose if instructed; report high readings.
  • Eat a diet with adequate calcium and vitamin D; ask about bone-density screening.
functions Clinical judgment case — missed doses

A client on prednisone 20 mg daily for 6 months had vomiting for 2 days and could not keep pills down. They are now dizzy, BP 84/50, HR 118. What does the nurse suspect?

  1. Recognize cues: long-term steroid use, missed doses, hypotension, tachycardia.
  2. Analyze: adrenal suppression plus sudden loss of steroid can cause adrenal crisis.
  3. Act: notify the provider immediately; anticipate IV fluids and IV hydrocortisone.
  4. Monitor glucose, sodium, and potassium.

Answer. Possible adrenal crisis. Notify the provider immediately and prepare for IV fluids and hydrocortisone.