Peripheral IV complications

Assess the site and the infusion every time you are in the room and per policy.

ComplicationFindingsNursing action
InfiltrationSwelling, coolness, pallor, slowed flow, no blood returnStop, remove, elevate, restart elsewhere; compress per policy
Extravasation (vesicant)Pain, burning, blanching, blisteringStop; follow protocol (often aspirate before removing); notify; antidote per protocol
PhlebitisRedness, warmth, tenderness, palpable cord along the veinRemove catheter; warm compress per policy; restart elsewhere
Local infectionRedness, drainage, feverRemove; culture per policy; notify
Fluid overloadCrackles, dyspnea, JVD, rising BP, weight gainSlow the infusion to keep-open rate, raise head of bed, notify
Air embolismSudden dyspnea, chest pain, hypotension, confusionClamp; left side, head down if tolerated; oxygen; rapid response

Common vesicants include many chemotherapy drugs, vasopressors such as norepinephrine, and concentrated calcium or potassium solutions.

InfiltrationFluid leaks into tissueCool, pale, swollenTaut skin around siteFlow slows or stopsRemove and elevatePhlebitisInflammation of the veinWarm, red, tenderRed streak or cordOften irritating drugsRemove; warm compress per policyvs
Cool vs warm. Temperature at the site is the fastest way to tell them apart.

Central venous access

Central lines deliver irritating drugs and TPN but carry a risk of bloodstream infection and air embolism.

Central venous accessNon-tunneledShort-term; jugular,subclavian, femoralPICCArm vein; weeks tomonthsTunneledLong-term; cuffunder skinImplanted portUnder skin;non-coring needle
Central venous access devices. Do not take blood pressure or draw blood with a tourniquet on the arm with a PICC.
  • Confirm catheter tip position before first use as required by policy (often by chest x-ray).
  • Prevent bloodstream infection: hand hygiene, chlorhexidine skin prep, sterile dressing changes, scrub the hub before each access, and remove lines that are no longer needed.
  • Prevent air embolism: clamp before changing caps or tubing; have the client perform a Valsalva maneuver (or exhale) during line removal, then apply an occlusive dressing.
  • Report fever, chills, or redness and drainage at the site; suspect a central line–associated bloodstream infection.

Total parenteral nutrition

TPN is a concentrated, high-glucose solution given through a central line.

VerifyOrder and bagcontentsDedicatedlineNothing elseinfusedPumpConstant rateMonitorGlucose,electrolytes,weightNeverstopabruptlyReboundhypoglycemia
TPN care. Do not speed up a TPN infusion that is behind schedule; it can cause hyperglycemia and fluid overload.
ComplicationClueAction
HyperglycemiaElevated glucose, thirst, polyuriaMonitor glucose; insulin as ordered
Rebound hypoglycemiaShaky, sweaty after TPN stopsTaper per order; hang dextrose 10% if TPN is unavailable, per policy
Refeeding syndromeLow phosphate, potassium, magnesium in malnourished clientsStart slowly; monitor and replace electrolytes
InfectionFever, line-site rednessAseptic technique; report

TPN tubing and bag changes follow facility policy (lipid-containing solutions have shorter hang times).

Starting and maintaining a peripheral IV

Technique questions test site selection and safety.

  • Choose distal sites first so later attempts can move proximal; avoid the arm on the side of a mastectomy or a dialysis fistula.
  • Use larger catheters (for example, 18–20 gauge) for rapid infusion or blood transfusion, per policy.
  • Label the site and tubing per policy; check patency before giving IV push medications.
  • Pumps do not replace site assessment: a pump keeps pushing fluid into tissue during infiltration.

NGN-style case

Order of actions matters.

functions Clinical judgment case — sudden dyspnea

While the nurse changes the tubing on a client's central line, the client suddenly becomes short of breath with chest pain, SpO₂ 86%, and BP 84/50. What should the nurse do first?

  1. Recognize cues: sudden respiratory and circulatory compromise during an open central line connection.
  2. Analyze: likely air embolism.
  3. Clamp the catheter to stop more air from entering.
  4. Position on the left side with head down if tolerated, give oxygen, call the rapid response team, and stay with the client.

Answer. Clamp the line first, then position left side with head down, give oxygen, and call for help.