How oxygen therapy is tested on the NCLEX-RN

Items fall under Physiological Adaptation, Safety, and Basic Care.

More oxygenNasal cannula1–6 L/min; comfortable; can eat and talkSimple mask5–10 L/min; minimum 5 L/minVenturi maskPrecise FiO₂ set by the adapterNon-rebreather10–15 L/min; keep bag inflatedHigh-flow / NIVHeated high-flow cannula, CPAP, BiPAP
Devices. Approximate ranges as commonly taught; follow manufacturer and facility guidance.

Recognize hypoxia

Behavioral changes often come before a falling SpO₂ is noticed.

Hypoxia cuesEarlyRestless, anxious,tachycardia, tachypneaLateCyanosis, bradycardia,confusion, stuporChronicClubbing, fatigue
Hypoxia cues. A newly confused older client should have oxygenation checked.
SpO₂ factorEffect
Poor perfusion, cold fingersUnreliable reading; try earlobe or forehead probe
Dark nail polish, artificial nailsCan interfere with reading
Carbon monoxide poisoningFalsely normal SpO₂
Darker skin pigmentationPulse oximeters can overestimate saturation; correlate with ABGs and clinical signs
MotionArtifact

Treat the client, not only the number.

Take action: titration and positioning

Match the device to the need and reassess.

AssessAirway, RR,SpO₂, mentalstatusPositionHead of bedupOxygenDevice perorder/protocolReassessSpO₂ and workof breathingEscalateIf notimproving
Low SpO₂ workflow. Check that tubing is connected and flowing before escalating.
  • Usual target is often 92–96% for many adults; for clients at risk of CO₂ retention (some COPD), often 88–92%, as ordered.
  • Humidification may be used at higher flows to reduce dryness.
  • Encourage deep breathing, incentive spirometry, and coughing as appropriate.

Safety and skin care

Oxygen supports combustion and devices can cause pressure injuries.

RiskNursing action
FireNo smoking, candles, or open flames; post signs; avoid petroleum jelly on the face (use water-based lubricant)
Tank safetySecure cylinders upright; store away from heat
Pressure injuryPad tubing over ears; check nares and bridge of nose
DrynessMouth care; humidify as ordered
Oxygen toxicityAvoid prolonged high FiO₂ beyond what is needed

Home oxygen clients also need teaching on flow settings and when to call.

NGN-style case

Device selection and troubleshooting.

functions Clinical judgment case — non-rebreather

A client on a non-rebreather mask at 15 L/min has SpO₂ 84%. The nurse notices the reservoir bag collapses completely when the client inhales. What should the nurse do?

  1. Recognize cues: low SpO₂ and a collapsing reservoir bag.
  2. Analyze: the bag is not staying inflated, so the client is not receiving the intended high FiO₂.
  3. Check the connection and flow; ensure the bag stays at least partly inflated on inhalation.
  4. Reassess SpO₂ and work of breathing; escalate to the rapid response team if not improving.

Answer. Check the oxygen connection and flow so the reservoir bag stays inflated, then reassess and escalate if hypoxemia persists.