How TB is tested on the NCLEX-RN

Items fall under Safety and Infection Prevention and Control and Pharmacological Therapies.

Latent TB infectionPositive skin test or IGRANo symptomsNormal chest x-rayNot contagiousTreated to prevent diseaseActive TB diseaseCough over 3 weeks, hemoptysisNight sweats, fever, weight lossAbnormal chest x-rayContagious (pulmonary)Multi-drug therapyvs
Latent vs active. Only active pulmonary or laryngeal TB requires airborne isolation.

Infection control

TB spreads through airborne droplet nuclei.

RoomNegative-pressure AIIRDoorKept closedStaffFit-testedN95TransportClient wearssurgical maskTeachCover cough,disposetissues
Airborne precautions. Isolation usually ends when the provider determines the client is no longer infectious, typically after effective treatment, clinical improvement, and negative sputum results per policy.

Screening tests

Reading a TB skin test is a classic NCLEX skill.

IndurationConsidered positive for
≥5 mmPeople with HIV, recent close contacts, immunosuppressed clients, abnormal chest x-ray consistent with prior TB
≥10 mmRecent arrivals from high-prevalence countries, people who inject drugs, residents and staff of high-risk settings, children under 4
≥15 mmPeople with no known risk factors

Measure only the raised, hardened area, not redness. A positive test shows infection, not necessarily active disease; a chest x-ray follows.

RIPE drug therapy

Know the signature adverse effect of each drug.

RIPE therapyRifampinOrange fluids;liver; druginteractionsIsoniazidLiver; neuropathy(give B6)PyrazinamideLiver; high uricacidEthambutolVision: acuity,red-green color
RIPE. Rifampin can reduce effectiveness of hormonal contraceptives and many other drugs.
MonitorReport
Liver function testsJaundice, dark urine, nausea, right upper quadrant pain
Vision (ethambutol)Blurred vision, trouble distinguishing red and green
Neuropathy (isoniazid)Numbness or tingling in hands or feet
AdherenceMissed doses; directly observed therapy may be used

Avoid alcohol during treatment because of liver toxicity.

NGN-style case and teaching

Teaching supports months of adherence.

functions Clinical judgment case — admission

A client is admitted with 4 weeks of productive cough, night sweats, and weight loss. Sputum results are pending. What should the nurse do first?

  1. Recognize cues: classic symptoms of active pulmonary TB.
  2. Analyze: the client may be infectious; precautions start on suspicion, not after confirmation.
  3. Place the client in an airborne infection isolation room; staff wear N95 respirators.
  4. Obtain sputum specimens as ordered (often early-morning samples) and notify infection prevention.

Answer. Initiate airborne precautions in a negative-pressure room right away, before results return.

  • Take medications exactly as prescribed for the full course, often 6 months or more.
  • Expect orange urine, sweat, and tears with rifampin; soft contact lenses can be stained.
  • Avoid alcohol; report yellow skin, dark urine, vision changes, or tingling.
  • Close contacts should be screened.